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Scientists have not long ago determined and succeeded in synthesizing conolidine, a pure compound that shows guarantee being a powerful analgesic agent with a more favorable protection profile. Although the specific system of action continues to be elusive, it can be at the moment postulated that conolidine could have several biologic targets. Pres… Read More

Most a short while ago, it has been determined that conolidine and the above derivatives act about the atypical chemokine receptor three (ACKR3. Expressed in similar areas as classical opioid receptors, it binds to some wide array of endogenous opioids. Contrary to most opioid receptors, this receptor acts to be a scavenger and does not activate a … Read More

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